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Richard N de Steiger, Brian R Hallstrom, Anne Lübbeke, Elizabeth W Paxton, Liza N van Steenbergen, and Mark Wilkinson

comparator being all prosthesis combinations that have similar features to the device being examined, i.e. if the device is a cementless stem/cup combinations in patients with procedures performed for primary osteoarthritis. The outlier alert boundary is set

Sylvain Steinmetz, Anne-Laure Rougemont, and Robin Peter

capsule or near the fovea. 16 Unlike in osteoarthritis, the lytic changes are not only secondary to a bone invasion of the outside of the weight-bearing area, but also due to intra-articular hyperpressure. The thick capsule that is physiologically

Anne Lübbeke

markers (e.g. current status of biomarkers for osteoarthritis and their use in approval studies 20 ) and biomechanical parameters (e.g. knee instability, 21 gait biomechanics in knee osteoarthritis 22 ). The use of surrogates instead of

Francisco Figueroa, David Figueroa, Rafael Calvo, Alex Vaisman, and João Espregueira-Mendes

defects, instability or malalignment should be amenable to surgical correction. On the other hand, classical contraindications are: advanced osteoarthritis, obesity, skeletal immaturity, inflammatory arthritis, previous septic arthritis, and synovial

Laurent Nové-Josserand

preferred to treat osteoarthritis and explains why total arthroplasty is contraindicated in patients with a high risk of glenoid loosening: i.e. those at risk of early loosening because of rotator cuff tear; young, active patients with a risk of early wear

Salvi Prat-Fabregat and Pilar Camacho-Carrasco

that, in some specific patients, TKA could be the primary procedure. Age > 65 years, local osteopaenia, corticoid use and pre-existing osteoarthritis are identified as the main reasons indicating a primary arthroplasty. What outcomes can be

Reinier Feitz, Yara E. van Kooij, Marloes H. P. ter Stege, Mark J. W. van der Oest, J. Sebastiaan Souer, Robbert M. Wouters, Harm P. Slijper, Ruud W. Selles, Steven E. R. Hovius, and Hand–Wrist Study Group

immobilization following surgery for thumb-base osteoarthritis. Specifically, we now give patients a cast for three to five days, followed by a removable thermoplastic orthosis. This allowed for earlier onset of hand therapy and more comfort after surgery for our

Nuno Marques Luís and Ricardo Varatojo

the anatomic tibiofemoral angle does not reproduce a correct estimation of the mechanical tibiofemoral angle. The anatomic tibiofemoral angle is valgus with an offset of 4–6° for healthy individuals. In patients with knee osteoarthritis, the anatomic

Keijo T. Mäkelä, Ove Furnes, Geir Hallan, Anne Marie Fenstad, Ola Rolfson, Johan Kärrholm, Cecilia Rogmark, Alma Becic Pedersen, Otto Robertsson, Annette W-Dahl, Antti Eskelinen, Henrik M. Schrøder, Ville Äärimaa, Jeppe V. Rasmussen, Björn Salomonsson, Randi Hole, and Søren Overgaard

with metal-on-metal (MoM) bearings and metal-on-polyethylene (MoP) bearings. Focus on fixation methods of primary THA Pedersen et al assessed 29 558 primary THRs on patients with osteoarthritis (OA), aged < 55 years, performed from 1995 to

Joost van Tilburg and Mikkel Rathsach Andersen

osteoarthritis (OA) and is known to disproportionally increase and accelerate knee arthrosis ( 4 , 5 , 6 , 7 ). Aging as well is correlated with OA ( 8 , 9 , 10 ), and since the world’s population is getting older, this further increases the demand for