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Junbo He Department of Orthopedic Surgery, West China Hospital, Sichuan University, Chengdu, China
These authors contributed equally to this work and should be considered co-first authors

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Tingkui Wu Department of Orthopedic Surgery, West China Hospital, Sichuan University, Chengdu, China
These authors contributed equally to this work and should be considered co-first authors

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Chen Ding Department of Orthopedic Surgery, West China Hospital, Sichuan University, Chengdu, China

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Beiyu Wang Department of Orthopedic Surgery, West China Hospital, Sichuan University, Chengdu, China

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Ying Hong West China School of Nursing, Sichuan University/ Department of Anesthesia and Operation Center, West China Hospital, Sichuan University, Chengdu, China

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Hao Liu Department of Orthopedic Surgery, West China Hospital, Sichuan University, Chengdu, China

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  • Anterior cervical surgery (ACS) owes its development to various pioneering individuals whose revolutionary works form key advances and guide current medical decisions. This bibliometric study aimed to identify, analyse and visualize the main features of the most-cited papers in ACS.

  • The citation count for the top 100 most-cited articles ranged from 148 to 1,197, and citations per year ranged from 3.1 to 89.8. The articles were published from 1958 to 2016, with the 2000s being the most active decade. There was an inverse correlation between the average citations per year since publication and article age.

  • The oldest as well as most-cited two articles were both published in 1958 by Smith and Robinson, and Cloward, respectively. In their studies, the authors individually described the technique of anterior cervical discectomy with fusion (ACDF).

  • The most popular keywords were: ‘fusion’ (22), ‘spine’ (20), ‘cervical spine’ (16), ‘complications’ (15), ‘arthrodesis’ (13), ‘interbody fusion’ (13), ‘bone morphogenetic protein’ (13), and ‘radiculopathy’ (12).

  • ACDF was the most frequent surgical procedure (80%), while cervical disc arthroplasty is of gradual greater impact.

  • The surgical techniques of ACDF have remained unaltered for over 60 years. More attempts are needed to promote its development.

Cite this article: EFORT Open Rev 2021;6:1203-1213. DOI: 10.1302/2058-5241.6.210074

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Xiaofeng Deng Department of Rehabilitation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

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Haoran Xu Department of Orthopedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

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Xiaoxia Hao Department of Rehabilitation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

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Jiawei Liu Department of Rehabilitation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

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Xingru Shang Department of Rehabilitation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

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Tao Xu Department of Rehabilitation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

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  • Osteoarthritis (OA) is a chronic degenerative disease, which can cause a series of symptoms including pain and functional limitation, thus severely decreasing quality of life.

  • OA pathogenesis can be categorized into four levels, including risk factors, potential mechanisms, intraarticular degeneration phenotype, and substantive histological changes.

  • Moderate exercise can alleviate OA at all levels of pathogenesis, while excessive exercise may have adverse effects.

  • Based on rat-related original research, the parameters of moderate exercise and the effect of improving osteoarthritis have been comprehensively summarized.

  • Based on the extensive randomized controlled trial studies, results show various moderate exercises can improve the symptom and prognosis of OA in clinical settings.

  • This review gives an overview of the pathogenesis of OA and the mechanisms as well as clinical examples of moderate exercise treatment, aimed at providing rationale and evidence for moderate exercise in the treatment of OA to facilitate the provision of appropriate exercise therapy for OA patients.

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Wen-xi Sun Guangzhou University of Chinese Medicine, Guangzhou, China

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Hao-nan Liu Guangzhou University of Chinese Medicine, Guangzhou, China

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Meng-tong Chen Guangzhou University of Chinese Medicine, Guangzhou, China

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Yong-peng Lin Division of Spine Center, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, China

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Hong-shen Wang Division of Spine Center, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, China

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Bo-lai Chen Guangzhou University of Chinese Medicine, Guangzhou, China
Division of Spine Center, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, China

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Objective

  • The aim of this study was to comprehensively evaluate the efficacy of oblique lateral interbody fusion (OLIF) and transforaminal lumbar interbody fusion (TLIF) in the treatment of degenerative lumbar spondylolisthesis by meta-analysis.

Methods

  • A computer-based search of PubMed, Cochrane Library, Embase, Web of Science Core Collection databases, the China National Knowledge Infrastructure, China Biology Medicine, and Wanfang Digital Periodicals was conducted from the time of inception of each database to December 2021. The review process was conducted according to the PRISMA guidelines and registered in the PROSPERO database. Meta-analysis was performed using RevMan 5.4 software provided by the Cochrane Library.

Results

  • Thirteen studies were included in the statistical analysis. One randomized controlled study and 12 cohort studies with 954 patients were included. In terms of operation time, intraoperative blood loss, Oswestry disability index score, intervertebral height, and complications, the OLIF group was better than the TLIF group, and the difference was statistically significant (P < 0.05). There was no significant difference between the two groups in terms of visual analogue scale score, lumbar lordosis or fused segment lordosis (P > 0.05).

Conclusion

  • Both OLIF and TLIF are effective surgical modalities in the treatment of degenerative lumbar spondylolisthesis. They achieve similar therapeutic effects, but OLIF is superior to TLIF in restoring intervertebral height. At the same time, OLIF has the advantages of short operation time and less intraoperative blood loss.

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