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  • Author: José Portela x
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Maria Beatriz Quaresma Orthopaedics Department, University Hospital Santa Maria – Centro Hospitalar Lisboa Norte, Lisbon, Portugal

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José Portela Orthopaedics Department, University Hospital Santa Maria – Centro Hospitalar Lisboa Norte, Lisbon, Portugal

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Joaquim Soares do Brito Orthopaedics Department, University Hospital Santa Maria – Centro Hospitalar Lisboa Norte, Lisbon, Portugal

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  • Diffuse-type tenosynovial giant-cell tumours of the knee (D-TGCT) have a very high complication rate.

  • The recurrence rate for D-TGCT is mainly dependent on an initially successful resection of the lesion.

  • The standard of care for this disease involves early surgery with synovectomy. Available surgical techniques may include an arthroscopic or open surgery; however, there is a lack of consensus on which technique should be used, and when.

  • Arthroscopic excision is effective in minimizing morbidity and surgery-related complications, while an open surgical technique provides a more successful resection with a lower incidence of local recurrence.

  • We could not conclude with confidence which of the surgical techniques is better at stopping a progression towards osteoarthritis and the need for a total knee arthroplasty.

Cite this article: EFORT Open Rev 2020;5:339-346. DOI: 10.1302/2058-5241.5.200005

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Joaquim Soares do Brito Orthopedics Department, University Hospital of Santa Maria, Lisbon, Portugal

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André Spranger Orthopedics Department, University Hospital of Santa Maria, Lisbon, Portugal

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Paulo Almeida Orthopedics Department, University Hospital of Santa Maria, Lisbon, Portugal

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José Portela Orthopedics Department, University Hospital of Santa Maria, Lisbon, Portugal

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Irene Barrientos-Ruiz Orthopedics Department, University Hospital of La Paz, Madrid

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  • Giant cell tumour of bone (GCT) is a relatively rare, locally aggressive benign neoplasm observed in the long bone epiphyseal-metaphyseal regions of young adults.

  • The optimal treatment strategy for these tumours remains controversial, and a huge amount of contradictory data regarding the functional and oncological outcomes can be found. Therefore, we performed a systematic review intended to investigate the functional and oncological outcomes after surgical treatment of GCTs arising around the knee, namely in the distal femur and proximal tibia.

  • A trend towards better oncological control was found using wide resections, nonetheless, curettage-based techniques achieve a highly acceptable recurrence rate with overall better knee function. A slight advantage favouring proximal tibia GCTs regarding the Musculoskeletal Tumor Society (MSTS) score was also observed.

  • Prospective studies comparing groups of more homogeneous patients, tumours, and treatment options should be developed to obtain more conclusive and definitive results regarding the optimal strategy for treating GCTs.

Cite this article: EFORT Open Rev 2021;6:641-650. DOI: 10.1302/2058-5241.6.200154

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